Reversible photopadlocking on double-stranded DNA.

نویسندگان

  • Kenzo Fujimoto
  • Shigeo Matsuda
  • Yoshinaga Yoshimura
  • Takehiro Ami
  • Isao Saito
چکیده

We describe a highly efficient method for reversible photocircularization of oligonucleotide (ODN) on a double-stranded DNA template: 5-carboxyvinyl-2'-deoxyuridine-containing ODN was reversibly circularized around the target sequence of the double-stranded plasmid DNA resulting in formation of a catenated plasmid.

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عنوان ژورنال:
  • Chemical communications

دوره 28  شماره 

صفحات  -

تاریخ انتشار 2007